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  • 产品名称：HepatitisBVirusSurfaceAntigen(HBSAg)(AA1-226)(Active)Protein

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  • 产品厂商：ACROBiosystems
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简单介绍：
HepatitisBVirusSurfaceAntigen(HBSAg)(AA1-226)(Active)Protein
详情介绍：
Characteristics rHBsAg-adw full length monomeric protein contains 226 amino acids (Met 1 - Ile 226) and the has a calculated MW of 24 kDa.The predicted N-terminus is Met.The reducing (R) protein migrates as 24 kDa in SDS-PAGE.
Purity >97 % as determined by SDS-PAGE.
Sterility 0.22 μm filtered
Endotoxin Level Less than 0.05 EU per μg by the LAL method.
Background Hepatitis B virus (HBV) is a human pathogen, causing serious liver disease. At the center of the hepatitis B virus is DNA, which contains the genes the virus uses to replicate itself. Surrounding the DNA is a protein called HBcAg (hepatitis B core antigen), which cannot be detected with blood tests. Surrounding this is HBsAg, which is actually part of the protective "envelope." This envelope surrounds the virus and protects it from attack by the body's immune system. HBsAg stands for hepatitis B surface antigen and is the surface antigen of the Hepatitis-B-Virus (HBV) S-gene. The capsid of a virus has different surface proteins from the rest of the virus. The antigen is a protein that binds specifically on one of these surface proteins. It is commonly referred to as the Australian Antigen.
Molecular Weight 24 kDa
Gene ID 17
Research Area Virology
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer PBS, pH 7.4
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Supplier Images
SDS-PAGE (SDS) image for Hepatitis B Virus Surface Antigen (HBSAg) (AA 1-226) (Active) Protein (ABIN2181196) HBV (Subtype adw) HBsAg on SDS-PAGE under reducing (R) condition. The gel was stained...
Product cited in: Aghasadeghi, Delbaz, Sadat, Siadat, Ardestani, Rahimi, Bolhassani, Roudsari, Bahramali, Motevalli, Davari, Vakily, Salmani, Nobari: "Induction of Strong and Specific Humoral and T-helper 1 Cellular Responses by HBsAg Entrapped in the Methanobrevibacter smithii Archaeosomes." in: Avicenna journal of medical biotechnology, Vol. 6, Issue 4, pp. 238-45, 2014 (PubMed).