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  • 产品名称：Syndecan1(SDC1)(AA23-254)(Active)protein(Histag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
Syndecan1(SDC1)(AA23-254)(Active)protein(Histag)
详情介绍：
Characteristics This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24.7 kDa. The protein migrates as 48-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity >92 % as determined by SDS-PAGE.
Sterility 0.22 μm filtered
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Syndecan-1 (SYND1 or SDC1) is also known as CD antigen CD138, is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 / SDC1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a useful marker for plasma cells, but only if the cells tested are already known to be derived from blood.
Molecular Weight 24.7 kDa
UniProt P18827
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer PBS, pH 7.4
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Supplier Images
SDS-PAGE (SDS) image for Syndecan 1 (SDC1) (AA 23-254) (Active) protein (His tag) (ABIN2180684) Human Syndecan-1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stain...
Background publications Rollett, Wilkinson, Gonzalez, Fenton, Short, Evans, Rawstron, Owen: "Immunoglobulin heavy chain sequence analysis in Waldenstrom's macroglobulinemia and immunoglobulin M monoclonal gammopathy of undetermined significance." in: Clinical lymphoma & myeloma, Vol. 7, Issue 1, pp. 70-2, 2006 (PubMed).

Bhatt, Erdjument-Bromage, Tempst, Craik, Moasser: "Adhesion signaling by a novel mitotic substrate of src kinases." in: Oncogene, Vol. 24, Issue 34, pp. 5333-43, 2005 (PubMed).