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  • 产品名称：FGF-9(AA4-208)(Active)protein(FcTag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
FGF-9(AA4-208)(Active)protein(FcTag)
详情介绍：
Characteristics This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 50.6 kDa. As a result of glycosylation, the protein migrates as 55 kDa under reducing (R) condition, and 110 kDa under non-reducing (NR) condition (SDS-PAGE).
Purity >92 % as determined by SDS-PAGE.
Sterility 0.22 μm filtered
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Fibroblast growth factor 9 is also known as FGF9, GAF, HBFG-9, SYNS3, and is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF9 is also a mitogen for oligodendrocyte type 2 astrocyte progenitor cells, smooth muscle cells, pheochromocytoma PC12 cells, and BALB/3T3 fibroblasts. However, unlike FGF acidic and basic, FGF9 has no effect on human umbilical vein endothelial cells, and it has been demonstrated that FGF9 binds preferentially to the IIIc form of FGFR3. Although no typical signal sequence was found in FGF9, it is secreted efficiently after synthesis not in a conventional manner. In nervous system, FGF9 is produced mainly by neurons and may plays an important role in CNS development. FGF9 has been shown to interact with Fibroblast growth factor receptor 3.
Molecular Weight 50.6 kDa
UniProt P31371
Research Area Growth Factors
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 50 mM Tris, 100 mM Glycine, pH 7.5
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Supplier Images
SDS-PAGE (SDS) image for FGF-9 (AA 4-208) (Active) protein (Fc Tag) (ABIN2181090) Human FGF-9, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. T...
Background publications Santos-Ocampo, Colvin, Chellaiah, Ornitz: "Expression and biological activity of mouse fibroblast growth factor-9." in: The Journal of biological chemistry, Vol. 271, Issue 3, pp. 1726-31, 1996 (PubMed).