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  • 产品名称:Rabbitanti-HumanIgG(Heavy&LightChain)Antibody

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  • 产品厂商:Acris-antibodies
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简单介绍:
Rabbitanti-HumanIgG(Heavy&LightChain)Antibody
详情介绍:
Characteristics The antiserum of individual host animals was monitored for titre and specificity before pooling into uniform high titre lots.
Against NHS: Single band at all dilutions up to 1/1024.
Against NMS: No bands at a dilution of 1/4.
Against Human IgG (5 mg/mL): Lot 0128 produced a single band homogeneous with a single band from NHS dilutions of 1/4 and 1/8.
Purification Serum
Background IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen s. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75 % of serum immunoglobulins in humans. This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. It can bind to many kinds of pathogens, for example viruses, bacteria, and fungi, and protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralisation of their toxins. There are 4 subclasses: IgG1 (66 %), IgG2 (23 %), IgG3 (7 %) and IgG4 (4 %).Synonyms: Human Immunoglobulin G
Research Area Immunology, Secondary Antibodies
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20 °C.