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  • 产品名称：anti-IL12Aantibody(Interleukin12alpha)(FITC)

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  • 产品厂商：Acris-antibodies
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简单介绍：
anti-IL12Aantibody(Interleukin12alpha)(FITC)
详情介绍：
Immunogen Recombinant Human IL-12.
Clone B-T21
Isotype IgG1
Specificity This antibody recognizes both natural and recombinant Human IL-12 p35 + p70
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ion Exchange Chromatography.
Alternative Name Interleukin-12 alpha / IL12A (IL12A Antibody Abstract)
Background Interleukin 12 (IL12) is an important cytokine produced by a variety of immune effector cells that leads to a type 1 helper T cell (Th1) response. IL12 also directs T cells to the skin via induction of cutaneous lymphocyte antigen (CLA) expression. Interleukin 12 is a heterodimeric cytokine (p70), composed of two covalently linked subunits, p35 and p40.Synonyms: CLMF p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL-12 subunit p35, IL-12A, NK cell stimulatory factor chain 1, NKSF1
Gene ID 3592
NCBI Accession NP_000873
UniProt P29459
Pathways JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer PBS containing 5 % BSA as stabilizer and 0.09 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.
Background publications Morandi, Levreri, Bocca, Galleni, Raffaghello, Ferrone, Prigione, Pistoia: "Human neuroblastoma cells trigger an immunosuppressive program in monocytes by stimulating soluble HLA-G release." in: Cancer research, Vol. 67, Issue 13, pp. 6433-41, 2007 (PubMed).