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  • 产品名称:anti-FcFragmentofIgE,LowAffinityII,ReceptorFor(CD23)(FCER2)antibody(PE)

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  • 产品厂商:Acris-antibodies
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简单介绍:
anti-FcFragmentofIgE,LowAffinityII,ReceptorFor(CD23)(FCER2)antibody(PE)
详情介绍:
Immunogen Fc ER isolated from the 01 2B2 cell line.
Clone 2G8
Isotype IgG2a
Specificity This antibody recognises the murine CD23 cell surface antigen, a 49 kDa glycoprotein expressed by most mature B cells, and also on some T cells, macrophages and platelets.
Alternative Name CD23 (FCER2 Antibody Abstract)
Background CD23 antigen is an integral membrane glycoprotein, Mr. 45 kdaltons. The CD23 antigen is present on approximately all pre-B lymphocytes, plasma cells CD25 positive Ki-1 cells and HLA-DR. CD23 antigen is also expressed on Lymphoma, T Cell Lymphomas and B-CLLs. CD23 antigen is present on Hodgkin's and Reed Sternberg cells.Synonyms: CD23A, FCE2, FCER2, Fc-epsilon-RII, IGEBF, Immunoglobulin E-binding factor, Low affinity immunoglobulin epsilon Fc receptor, Lymphocyte IgE receptor
Gene ID 14128
NCBI Accession NP_038545
UniProt P20693
Research Area Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Application Notes Flow Cytometry: Use 10 μL of neat-1/10 diluted antibody to label 106 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice This product is photosensitive and should be protected from light
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Background publications Rao, Lee, Conrad: "Characterization of a monoclonal antibody directed against the murine B lymphocyte receptor for IgE." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 138, Issue 6, pp. 1845-51, 1987 (PubMed).