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  • 产品名称：anti-CD200antibody(CD200Molecule)(FITC)

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  • 产品厂商：Acris-antibodies
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简单介绍：
anti-CD200antibody(CD200Molecule)(FITC)
详情介绍：
Immunogen Rat thymocyte membrane glycoproteins. Spleen cells from immunised BALB/c mice were fused with cells from the NS1 mouse myeloma cell line.
Clone OX-2
Isotype IgG1
Specificity This antibody recognises the CD200 cell surface antigen, also known as OX-2. This product is routinely tested by flow cytometry on rat thymocytes.
Purification Affinity chromatography on Protein G
Alternative Name CD200 (CD200 Antibody Abstract)
Background CD200 is a type I membrane glycoprotein, expressed on rat thymocytes, neurons, follicular dendritic cells, endothelium and at low levels on some B cells and smooth muscle cells. Studies have indicated that the CD200-CD200 ligand system is important in the control of macrophage and granulocyte activation and that this antibody blocks OX-2 mediated T cell costimulation.Synonyms: MOX1, MOX2, My033, OX-2 membrane glycoprotein
Gene ID 24560
NCBI Accession NP_113706
UniProt P04218
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry: We recommend the use of ABIN120525 for use in functional studies.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Barclay, Ward: "Purification and chemical characterisation of membrane glycoproteins from rat thymocytes and brain, recognised by monoclonal antibody MRC OX 2." in: European journal of biochemistry / FEBS, Vol. 129, Issue 2, pp. 447-58, 1983 (PubMed).

Barclay: "Different reticular elements in rat lymphoid tissue identified by localization of Ia, Thy-1 and MRC OX 2 antigens." in: Immunology, Vol. 44, Issue 4, pp. 727-36, 1982 (PubMed).

Barclay: "The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues." in: Immunology, Vol. 42, Issue 4, pp. 593-600, 1981 (PubMed).

McMaster, Williams: "Identification of Ia glycoproteins in rat thymus and purification from rat spleen." in: European journal of immunology, Vol. 9, Issue 6, pp. 426-33, 1980 (PubMed).