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  • 产品名称：anti-CD38antibody(FITC)

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  • 产品厂商：Acris-antibodies
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简单介绍：
anti-CD38antibody(FITC)
详情介绍：
Immunogen Mouse pre-B cells derived from IL-7 dependent bone marrow cultures. Lymph node cells from an immunised rat were fused with cells of the mouse P3X63Ag.8.653 myeloma cell line.
Clone 90
Isotype IgG2a
Specificity This antibody recognises the CD38 cell surface antigen.
Background CD38 antigen is an integral membrane glycoprotein (M.W. 45 kD). The CD38 antigen is present on approximately all pre-B lymphocytes, plasma cells and thymocytes. CD38 antigen is also expressed on activated T Lymphocytes, NK Cells, monocytes, myeloblasts and erythroblasts. CD38 is co-expressed on CD34+ cells, but is not expressed on pluripotent stem cells. CD38 antigen is present on T and B lymphoblastic leukemia (ALL), Burkitts' lymphoma, multiple myeloma and acute myeloid leukemia (AML).Synonyms: ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, T10, cADPr hydrolase 1
Gene ID 12494
NCBI Accession NP_031672
UniProt P56528
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry: Use 10 μL of neat-1/10 diluted antibody to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer PBS containing 0.09 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Oliver, Martin, Kearney: "Mouse CD38 is down-regulated on germinal center B cells and mature plasma cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 3, pp. 1108-15, 1997 (PubMed).

Lund, Solvason, Grimaldi, Parkhouse, Howard: "Murine CD38: an immunoregulatory ectoenzyme." in: Immunology today, Vol. 16, Issue 10, pp. 469-73, 1995 (PubMed).