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  • 产品名称：anti-CD8antibody(PE)

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  • 产品厂商：Acris-antibodies
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简单介绍：
anti-CD8antibody(PE)
详情介绍：
Immunogen Normal human peripheral blood lymphocytes. Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63.653 myeloma cell line.
Clone LT8
Isotype IgG1
Specificity This antibody recognises the alpha-chain of the CD8 antigen.
Purification Ion Exchange Chromatography.
Background CD8 is a 32kD glycoprotein expressed by the cytotoxicsuppressor subset of T cells and weakly by NK cells. CD8 functions as a receptor for MHC Class I molecules.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
Gene ID 925
NCBI Accession NP_001759
UniProt P01732
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Reconstitution Restore with 1 mL distilled water.
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice This product is photosensitive and should be protected from light
Storage 4 °C
Storage Comment Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Background publications Manninen, Saksela: "HIV-1 Nef interacts with inositol trisphosphate receptor to activate calcium signaling in T cells." in: The Journal of experimental medicine, Vol. 195, Issue 8, pp. 1023-32, 2002 (PubMed).