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  • 产品名称：anti-ICAM2antibody(IntercellularAdhesionMolecule2)(FITC)

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  • 产品厂商：Acris-antibodies
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简单介绍：
anti-ICAM2antibody(IntercellularAdhesionMolecule2)(FITC)
详情介绍：
Immunogen Transfected COS cells expressing ICAM-2 cDNA. Cells from immunised BALB/c mice were fused with cells of the Murine P3X63Ag.653 myeloma cell line.
Clone CBRIC2-2
Isotype IgG2a
Specificity This antibody recognises CD102, also known as intercellular adhesion molecule-2 (ICAM-2). Clone CBR-IC2/2 is reported to inhibit interactions between CD102 and LFA-1. We recommend the use of SM2223LE for this purpose.
Purification Affinity Chromatography on Protein G.
Alternative Name CD102 / ICAM2 (ICAM2 Antibody Abstract)
Background CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is strongly expressed by endothelial cells. CD102 interacts with the CD11a/CD18 (LFA-1). Reports suggest that the CD102 may play a role in lymphocyte re-circulation and T-cell activation.Synonyms: ICAM-2, Intercellular adhesion molecule 2
Gene ID 3384
NCBI Accession NP_000864
UniProt P13598
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry (Neat-1/10): Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications de Fougerolles, Stacker, Schwarting, Springer: "Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1." in: The Journal of experimental medicine, Vol. 174, Issue 1, pp. 253-67, 1991 (PubMed).