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  • 产品名称：anti-CD8Bantibody(CD8bMolecule)(PE)

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  • 产品厂商：Acris-antibodies
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简单介绍：
anti-CD8Bantibody(CD8bMolecule)(PE)
详情介绍：
Immunogen Rat/mouse T cell hyrids expressing CD8. Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63 Ag.653 myeloma cell line.
Clone 341
Isotype IgG1
Specificity This antibody recognises the b chain of the rat CD8 cell surface antigen. This antibody is reported to block proliferative and cytotoxic responses of CD8 +ve effector cells in vitro.
Purification Affinity chromatography on Protein G
Alternative Name CD8 beta (CD8B Antibody Abstract)
Background CD8 is expressed on thymocytes and peripheral cytotoxic/suppressor cells. CD8b is not expressed by NK cells or by intestinal intraepithelial T cells.Synonyms: CD8B, CD8B1, T-cell surface glycoprotein CD8 beta chain
Gene ID 24931
NCBI Accession NP_113727
UniProt P05541
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling
Application Notes Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Reconstitution Restore with 1 mL distilled water
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage RT/4 °C/-20 °C
Storage Comment Lyophilized: Store at 2-8 °C (preferably in a dessicator). Reconstituted: Aliquot and store at -20 °C.
Background publications Torres-Nagel, Kraus, Brown, Tiefenthaler, Mitnacht, Williams, Hünig: "Differential thymus dependence of rat CD8 isoform expression." in: European journal of immunology, Vol. 22, Issue 11, pp. 2841-8, 1992 (PubMed).