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  • 产品名称：anti-VSIG1antibody(V-SetandImmunoglobulinDomainContaining1)(FITC)

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  • 产品厂商：Acris-antibodies
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简单介绍：
anti-VSIG1antibody(V-SetandImmunoglobulinDomainContaining1)(FITC)
详情介绍：
Immunogen Chicken thymocytes.
Clone CT1
Isotype IgG1
Specificity This antibody is specific to ChT1 antigen (Mr 63/104 kDa) on Chicken thymocyte. (Ref.1) CT1 can block T cell differentiation in vitro, in thymic organ cultures and in thymocyte precursors cultured on stromal cell monolayers. (Ref.4) CT1 also recognizes quail cortical thymocytes. (Ref.1)
Characteristics Synonyms: Cell surface A33 antigen, Glycoprotein A34, GPA34, V-set and immunoglobulindomain-containing protein 1
Alternative Name VSIG1 (VSIG1 Antibody Abstract)
Background ChT1, a member of the Ig superfamily with one V-like and one C2-like domain, is a T cell antigen that is expressed on the surface of embryonic thymocytes (day 10). In young chickens, about 90 % of the thymocytes as well as a subpopulation of peripheral lymphocytes (which represent recent thymic emigrants) are ChT1 positive. (Ref.1-4) Expression in the periphery declines with age and, in correlation with partial thymectomy, indicates that ChT1 can be used as an accurate marker for studying thymic function. (Ref.3)Synonyms: Cell surface A33 antigen, GPA34, Glycoprotein A34, V-set and immunoglobulin domain-containing protein 1
Gene ID 414795
UniProt Q9PWR4
Application Notes Flow Cytometry: < / = 1 μg/10^6 cells. Identification and enumeration of ChT1+ cells. (Ref.4)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS containing 0.09 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
Flow Cytometry (FACS) image for anti-VSIG1 antibody (V-Set and Immunoglobulin Domain Containing 1) (FITC) (ABIN371445) anti-V-Set and Immunoglobulin Domain Containing 1 (VSIG1) antibody (FITC)
Background publications Katevuo, Imhof, Boyd, Chidgey, Bean, Dunon, Göbel, Vainio: "ChT1, an Ig superfamily molecule required for T cell differentiation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 10, pp. 5685-94, 1999 (PubMed).

Kong, Chen, Cooper: "Thymic function can be accurately monitored by the level of recent T cell emigrants in the circulation." in: Immunity, Vol. 8, Issue 1, pp. 97-104, 1998 (PubMed).

Houssaint, Diez, Jotereau: "Tissue distribution and ontogenic appearance of a chicken T lymphocyte differentiation marker." in: European journal of immunology, Vol. 15, Issue 3, pp. 305-8, 1985 (PubMed).