产品详情
所在位置: 首页> 产品目录> 一抗>
查看大图

  • 产品名称：anti-CD1aMolecule(CD1A)antibody(FITC)

  • 产品型号：
  • 产品厂商：Acris-antibodies
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
anti-CD1aMolecule(CD1A)antibody(FITC)
详情介绍：
Clone MCD1a
Isotype IgG1
Specificity This antibody recognizes the largest (49 kDa) of the three variants of the CD1 heavy chain, designated as CD1a. The 49 kDa polypeptide is associated with b2-microglobulin on human cortical thymocytes, dendritic cells and Langerhans' cells. It may also be expressed on some T cell leukemias and lymphoma. The antibody does not react with peripheral blood T and B lymphocytes, monocytes, normal bone marrow mononuclear cells or normal tonsillar T and B lymphocytes.
Purification Affinity chromatography
Alternative Name CD1a (CD1A Antibody Abstract)
Background CD1a antigen is expressed on human cortical thymocytes, dendritic cells in peripheral lymph nodes and Langerhans' cells in normal, dysplastic and neoplastic tissue. CD1 has a domain organisation similar to that of MHC Class I and its expression is inversely correlated with that of TCR and MHC Class I.Synonyms: T-cell surface antigen T6/Leu-6, T-cell surface glycoprotein CD1a, T6/Leu-6, hTa1, hTa1 thymocyte antigen
Gene ID 909
NCBI Accession NP_001754
UniProt P06126
Research Area Immunology, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. This product is photosensitive and should be protected from light.
Supplier Images
image for anti-CD1a Molecule (CD1A) antibody (FITC) (ABIN1106008) anti-CD1a Molecule (CD1A) antibody (FITC)
Background publications Stein, Gerdes, Schwab, Lemke, Mason, Ziegler, Schienle, Diehl: "Identification of Hodgkin and Sternberg-reed cells as a unique cell type derived from a newly-detected small-cell population." in: International journal of cancer. Journal international du cancer, Vol. 30, Issue 4, pp. 445-59, 1983 (PubMed).

Boyden: "Natural antibodies and the immune response." in: Advances in immunology, Vol. 5, pp. 1-28, 1970 (PubMed).