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  • 产品名称：anti-KLRB1antibody(KillerCellLectin-LikeReceptorSubfamilyB,Member1)(PE)

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  • 产品厂商：Acris-antibodies
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简单介绍：
anti-KLRB1antibody(KillerCellLectin-LikeReceptorSubfamilyB,Member1)(PE)
详情介绍：
Immunogen Spleen cells from immunised BALB/c mice were fused with cells of the mouse P2X63.Ag8.653 myeloma cell line.
Clone B199-2
Isotype IgG2b
Specificity This antibody recognises the CD161 cell surface antigen. Clone B199.2 recognises a similar epitope to the DX9 monoclonal antibody.
Purification Affinity chromatography on Protein G
Alternative Name CD161 / KLRB1 (KLRB1 Antibody Abstract)
Background CD161 is expressed by almost all NK cells and with a small subset of CD3+ve T cells. CD161 is a homodimeric cell surface protein, comprising two chains of 40-44kD.Synonyms: C-type lectin domain family 5 member B, CLEC5B, HNKR-P1a, Killer cell lectin-like receptor subfamily B member 1, NKRP1A, Natural killer cell surface protein P1A
Gene ID 3820
NCBI Accession NP_002249
UniProt Q12918
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Reconstitution Restore with 1 mL distilled water
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice This product is photosensitive and should be protected from light
Storage 4 °C
Storage Comment Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!
Background publications Azzoni, Zatsepina, Abebe, Bennett, Kanakaraj, Perussia: "Differential transcriptional regulation of CD161 and a novel gene, 197/15a, by IL-2, IL-15, and IL-12 in NK and T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 7, pp. 3493-500, 1998 (PubMed).

Bennett, Zatsepina, Zamai, Azzoni, Mikheeva, Perussia: "Definition of a natural killer NKR-P1A+/CD56-/CD16- functionally immature human NK cell subset that differentiates in vitro in the presence of interleukin 12." in: The Journal of experimental medicine, Vol. 184, Issue 5, pp. 1845-56, 1996 (PubMed).