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  • 产品名称：anti-CEACAM5antibody(CarcinoembryonicAntigen-RelatedCellAdhesionMolecule5)(FITC

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  • 产品厂商：Acris-antibodies
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简单介绍：
anti-CEACAM5antibody(CarcinoembryonicAntigen-RelatedCellAdhesionMolecule5)(FITC)
详情介绍：
Immunogen Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3NSI myeloma cell line.
Clone C365D3 (NCRC23)
Isotype IgG1
Specificity This antibody recognises carcinoembryonic antigen. The antibody does not cross-react with normal crossreacting antigen (NCA), or with biliary glycoprotein (BGP).
Purification Affinity Chromatography on Protein G
Alternative Name CD66e / CEACAM5 (CEACAM5 Antibody Abstract)
Background Carcino Embryonic Antigen (CEA) is synthesised during development in the fetal gut, and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. Antibodies to CEA are useful in identifying the origin of various metastatic adenocarcinomas and in distinguishing pulmonary adenocarcinomas (60 to 70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+).Synonyms: CEA, Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, Meconium antigen 100
Gene ID 1048
NCBI Accession NP_004354
UniProt P06731
Research Area Cancer, Receptors, Immunology, Cell/Tissue Markers, CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer PBS, pH 7.4, 0.09 % Sodium Azide, 1 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Soucek, Gajdusková, Brázdová, Hýzdalová, Kocí, Vydra, Trojanec, Pernicová, Lentvorská, Hajdúch, Hofmanová, Kozubík: "Fetal colon cell line FHC exhibits tumorigenic phenotype, complex karyotype, and TP53 gene mutation." in: Cancer genetics and cytogenetics, Vol. 197, Issue 2, pp. 107-16, 2010 (PubMed).

Price: "Epitopes of carcinoembryonic antigen (CEA) defined by monoclonal antibodies." in: British journal of cancer, Vol. 57, Issue 2, pp. 165-9, 1988 (PubMed).